I think Clinton will likely get 341 electoral votes, Trump at will likely get 197. With Clinton reaching 273 at a minimum, this would place her in the White House. Trump would need to hope all of Clinton’s medical concerns are valid and take a sudden turn for the worse for him to have a chance.
Now for the challengers, both Governor Gary Johnson (L) and Jill Stein (G) will be on the ballot in most states in 2016. The Libertarian Party is on the ballot in all 50 states while the Green Party will be on many of them but missed crucial deadlines for some states. Obtaining ballot access is tough work. In polls where Governor Gary Johnson and Jill Stein were included, the polling gap between Clinton and Trump narrowed. The other candidate of notice is Evan McMullin (I) who is polling well in Utah but largely unknown and on only eleven ballots elsewhere. The former CIA spy could potentially shift Utah to voting in favor of Clinton or himself, largely due to his religious affiliation. This however will not impact the election much as Trump is in a large deficit with electoral votes. For McMullin I would guess this showing would catapult him in a position with establishment Republicans potentially setting him up for office in Utah. When it comes to national totals of the various challengers, Gary Johnson should come in the lead getting more than 5% of the vote leading to the Libertarian Party obtaining minor party status with better funding and ballot access for the next Presidential election.